Qube

Qube is Rome’s biggest LGBTQ+ nightclub, spread across three industrial-chic floors near Via di Portonaccio, each spinning a different genre from house to hip-hop to retro disco. The long-running Muccassassina party has anchored the scene here for two decades and still draws a mixed, high-energy crowd on weekend nights. Doors don’t get going until close to midnight and run through 3:30am Thursday to Saturday. Bring cash for the cover charge and coat check, and budget extra time for the line.